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Novel recognition motifs and biological functions of the RNA-binding protein HuD revealed by genome-wide identification of its targets
HuD is a neuronal ELAV-like RNA-binding protein (RBP) involved in nervous system development, regeneration, and learning and memory. This protein stabilizes mRNAs by binding to AU-rich instability elements (AREs) in their 3′ unstranslated regions (3′ UTR). To isolate its in vivo targets, messenger r...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800223/ https://www.ncbi.nlm.nih.gov/pubmed/19846595 http://dx.doi.org/10.1093/nar/gkp863 |