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Sequence context outside the target region influences the effectiveness of miR-223 target sites in the RhoB 3′UTR
MicroRNAs (miRNAs) are 21–22 nucleotide regulatory small RNAs that repress message translation via base-pairing with complementary sequences in the 3′ untranslated region (3′UTR) of targeted transcripts. To date, it is still difficult to find a true miRNA target due to lack of a clear understanding...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800228/ https://www.ncbi.nlm.nih.gov/pubmed/19850724 http://dx.doi.org/10.1093/nar/gkp870 |