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Two Dosages of Oral Fluoropyrimidine S-1 of 35 and 40 mg/m(2) bid: Comparison of the Pharmacokinetic Profiles in Korean Patients with Advanced Gastric Cancer

OBJECTIVE: In this study, we compared the pharmacokinetic profiles of 5-fluorouracil (5-FU), tegafur, 5-chloro-2,4-dihydroxypyridine (CDHP) and potassium oxonate (Oxo) after administration of S-1 at 35 or 40 mg/m(2) bid for 28 consecutive days, in Cycles 1 and 3, in patients with advanced gastric ca...

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Detalles Bibliográficos
Autores principales: Jeung, Hei-Cheul, Rha, Sun Young, Shin, Sang Joon, Ahn, Joong Bae, Noh, Sung Hoon, Roh, Jae Kyung, Chung, Hyun Cheol
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800316/
https://www.ncbi.nlm.nih.gov/pubmed/19880858
http://dx.doi.org/10.1093/jjco/hyp124