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Effect of NMSO3 treatment in a murine model of human metapneumovirus infection

BALB/c mice infected with human metapneumovirus (hMPV) were treated with the sulfated sialyl lipid NMSO3 (one dose of 50 mg kg(−1)) given at the time of infection. NMSO3 significantly reduced viral replication in the lungs, as well as hMPV-induced body weight loss, pulmonary inflammation and cytokin...

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Detalles Bibliográficos
Autores principales: Spetch, Leanne, Bowlin, Terry L., Casola, Antonella
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800786/
https://www.ncbi.nlm.nih.gov/pubmed/18931066
http://dx.doi.org/10.1099/vir.0.2008/003301-0