5-Lipoxygenase DNA Methylation and mRNA Content in the Brain and Heart of Young and Old Mice

The expression of 5-lipoxygenase (5-LOX) is affected by aging and regulated by epigenetic mechanisms including DNA methylation. We used methylation-sensitive restriction endonucleases (AciI, BstUI, HpaII, and HinP1I) to assess 5-LOX DNA methylation in brain and heart tissue samples from young (2 mon...

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Detalles Bibliográficos
Autores principales: Dzitoyeva, Svetlana, Imbesi, Marta, Ng, Louisa W., Manev, Hari
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801004/
https://www.ncbi.nlm.nih.gov/pubmed/20052386
http://dx.doi.org/10.1155/2009/209596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801004/
https://www.ncbi.nlm.nih.gov/pubmed/20052386
http://dx.doi.org/10.1155/2009/209596

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