Mousepox in the C57BL/6 strain provides an improved model for evaluating anti-poxvirus therapies

The intranasal lethal mousepox model employing the A/Ncr mouse strain is used to evaluate anti-orthopoxvirus therapies. These infections mimic large droplet transmission and result in 100% mortality within 7-10 days with as little as 1 PFU of ectromelia virus. Unlike the A/Ncr model, humans are less...

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Detalles Bibliográficos
Autores principales: Parker, Scott, Siddiqui, Akbar M., Oberle, Christina, Hembrador, Ed, Lanier, Randall, Painter, George, Robertson, Alice, Buller, R. Mark
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801418/
https://www.ncbi.nlm.nih.gov/pubmed/19100593
http://dx.doi.org/10.1016/j.virol.2008.11.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801418/
https://www.ncbi.nlm.nih.gov/pubmed/19100593
http://dx.doi.org/10.1016/j.virol.2008.11.015

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