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Mousepox in the C57BL/6 strain provides an improved model for evaluating anti-poxvirus therapies
The intranasal lethal mousepox model employing the A/Ncr mouse strain is used to evaluate anti-orthopoxvirus therapies. These infections mimic large droplet transmission and result in 100% mortality within 7-10 days with as little as 1 PFU of ectromelia virus. Unlike the A/Ncr model, humans are less...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801418/ https://www.ncbi.nlm.nih.gov/pubmed/19100593 http://dx.doi.org/10.1016/j.virol.2008.11.015 |