Glinide, but Not Sulfonylurea, Can Evoke Insulin Exocytosis by Repetitive Stimulation: Imaging Analysis of Insulin Exocytosis by Secretagogue-Induced Repetitive Stimulations

To investigate the different effects between sulfonylurea (SU) and glinide drugs in insulin secretion, pancreatic β-cells were repeatedly stimulated with SU (glimepiride) or glinide (mitiglinide). Total internal reflection fluorescent (TIRF) microscopy revealed that secondary stimulation with glimep...

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Detalles Bibliográficos
Autores principales: Aoyagi, Kyota, Ohara-Imaizumi, Mica, Nishiwaki, Chiyono, Nakamichi, Yoko, Nagamatsu, Shinya
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801449/
https://www.ncbi.nlm.nih.gov/pubmed/20069052
http://dx.doi.org/10.1155/2009/278762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801449/
https://www.ncbi.nlm.nih.gov/pubmed/20069052
http://dx.doi.org/10.1155/2009/278762

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