RNA interference as a gene silencing therapy for mutant MYOC protein in primary open angle glaucoma

BACKGROUND: Primary open-angle glaucoma (POAG) is the most common form of glaucoma which is an irreversible blind leading disease and lacks effective remedies. In recent years, POAG has been linked to the gene MYOC encoding myocilin that has been identified to harbor causal mutations. A variety of s...

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Detalles Bibliográficos
Autores principales: Li, Mao, Xu, Jianjiang, Chen, Xueli, Sun, Xinghuai
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801471/
https://www.ncbi.nlm.nih.gov/pubmed/20015381
http://dx.doi.org/10.1186/1746-1596-4-46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801471/
https://www.ncbi.nlm.nih.gov/pubmed/20015381
http://dx.doi.org/10.1186/1746-1596-4-46

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