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RNA interference as a gene silencing therapy for mutant MYOC protein in primary open angle glaucoma
BACKGROUND: Primary open-angle glaucoma (POAG) is the most common form of glaucoma which is an irreversible blind leading disease and lacks effective remedies. In recent years, POAG has been linked to the gene MYOC encoding myocilin that has been identified to harbor causal mutations. A variety of s...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801471/ https://www.ncbi.nlm.nih.gov/pubmed/20015381 http://dx.doi.org/10.1186/1746-1596-4-46 |