Biochemical evidence for the tyrosine involvement in cationic intermediate stabilization in mouse β-carotene 15, 15'-monooxygenase

BACKGROUND: β-carotene 15,15'-monooxygenase (BCMO1) catalyzes the crucial first step in vitamin A biosynthesis in animals. We wished to explore the possibility that a carbocation intermediate is formed during the cleavage reaction of BCMO1, as is seen for many isoprenoid biosynthesis enzymes, a...

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Detalles Bibliográficos
Autores principales: Poliakov, Eugenia, Gentleman, Susan, Chander, Preethi, Cunningham, Francis X, Grigorenko, Bella L, Nemuhin, Alexander V, Redmond, T Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801523/
https://www.ncbi.nlm.nih.gov/pubmed/20003456
http://dx.doi.org/10.1186/1471-2091-10-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801523/
https://www.ncbi.nlm.nih.gov/pubmed/20003456
http://dx.doi.org/10.1186/1471-2091-10-31

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