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Overexpression of CD97 in Intestinal Epithelial Cells of Transgenic Mice Attenuates Colitis by Strengthening Adherens Junctions

The adhesion G-protein-coupled receptor CD97 is present in normal colonic enterocytes but overexpressed in colorectal carcinoma. To investigate the function of CD97 in colorectal carcinogenesis, transgenic Tg(villin-CD97) mice overexpressing CD97 in enterocytes were generated and subjected to azoxym...

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Detalles Bibliográficos
Autores principales: Becker, Susann, Wandel, Elke, Wobus, Manja, Schneider, Rick, Amasheh, Salah, Sittig, Doreen, Kerner, Christiane, Naumann, Ronald, Hamann, Joerg, Aust, Gabriela
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801611/
https://www.ncbi.nlm.nih.gov/pubmed/20084281
http://dx.doi.org/10.1371/journal.pone.0008507