Cdk4 Regulates Recruitment of Quiescent β-Cells and Ductal Epithelial Progenitors to Reconstitute β-Cell Mass

Insulin-producing pancreatic islet β cells (β-cells) are destroyed, severely depleted or functionally impaired in diabetes. Therefore, replacing functional β-cell mass would advance clinical diabetes management. We have previously demonstrated the importance of Cdk4 in regulating β-cell mass. Cdk4-d...

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Detalles Bibliográficos
Autores principales: Lee, Ji-Hyeon, Jo, Junghyo, Hardikar, Anandwardhan A., Periwal, Vipul, Rane, Sushil G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801612/
https://www.ncbi.nlm.nih.gov/pubmed/20084282
http://dx.doi.org/10.1371/journal.pone.0008653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801612/
https://www.ncbi.nlm.nih.gov/pubmed/20084282
http://dx.doi.org/10.1371/journal.pone.0008653

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