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Multi-Platform Whole-Genome Microarray Analyses Refine the Epigenetic Signature of Breast Cancer Metastasis with Gene Expression and Copy Number

BACKGROUND: We have previously identified genome-wide DNA methylation changes in a cell line model of breast cancer metastasis. These complex epigenetic changes that we observed, along with concurrent karyotype analyses, have led us to hypothesize that complex genomic alterations in cancer cells (de...

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Detalles Bibliográficos
Autores principales: Andrews, Joseph, Kennette, Wendy, Pilon, Jenna, Hodgson, Alexandra, Tuck, Alan B., Chambers, Ann F., Rodenhiser, David I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801616/
https://www.ncbi.nlm.nih.gov/pubmed/20084286
http://dx.doi.org/10.1371/journal.pone.0008665