An efficient algorithm to compute marginal posterior genotype probabilities for every member of a pedigree with loops

BACKGROUND: Marginal posterior genotype probabilities need to be computed for genetic analyses such as geneticcounseling in humans and selective breeding in animal and plant species. METHODS: In this paper, we describe a peeling based, deterministic, exact algorithm to compute efficiently genotype p...

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Detalles Bibliográficos
Autores principales: Totir, Liviu R, Fernando, Rohan L, Abraham, Joseph
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801663/
https://www.ncbi.nlm.nih.gov/pubmed/19958551
http://dx.doi.org/10.1186/1297-9686-41-52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801663/
https://www.ncbi.nlm.nih.gov/pubmed/19958551
http://dx.doi.org/10.1186/1297-9686-41-52

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