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An efficient algorithm to compute marginal posterior genotype probabilities for every member of a pedigree with loops
BACKGROUND: Marginal posterior genotype probabilities need to be computed for genetic analyses such as geneticcounseling in humans and selective breeding in animal and plant species. METHODS: In this paper, we describe a peeling based, deterministic, exact algorithm to compute efficiently genotype p...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801663/ https://www.ncbi.nlm.nih.gov/pubmed/19958551 http://dx.doi.org/10.1186/1297-9686-41-52 |