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An improved empirical bayes approach to estimating differential gene expression in microarray time-course data: BETR (Bayesian Estimation of Temporal Regulation)

BACKGROUND: Microarray gene expression time-course experiments provide the opportunity to observe the evolution of transcriptional programs that cells use to respond to internal and external stimuli. Most commonly used methods for identifying differentially expressed genes treat each time point as i...

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Detalles Bibliográficos
Autores principales: Aryee, Martin J, Gutiérrez-Pabello, José A, Kramnik, Igor, Maiti, Tapabrata, Quackenbush, John
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801687/
https://www.ncbi.nlm.nih.gov/pubmed/20003283
http://dx.doi.org/10.1186/1471-2105-10-409