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Receptor Type Protein Tyrosine Phosphatase-Kappa Mediates Cross-Talk between Transforming Growth Factor-Beta and Epidermal Growth Factor Receptor Signaling Pathways in Human Keratinocytes

Epidermal growth factor receptor (EGFR) signaling pathways promote human keratinocyte survival and proliferation. In contrast, transforming growth factor-beta (TGF-β) signaling pathways are strongly anti-proliferative. Receptor type protein tyrosine phosphatase-kappa (RPTP-κ) specifically dephosphor...

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Detalles Bibliográficos
Autores principales: Xu, Yiru, Baker, Dustin, Quan, TaiHao, Baldassare, Joseph J., Voorhees, John J., Fisher, Gary J.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801716/
https://www.ncbi.nlm.nih.gov/pubmed/19864455
http://dx.doi.org/10.1091/mbc.E09-08-0710