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The Study of the Inhibition of the Recombinant TACE Prodomain to Endotoxemia in Mice

OBJECTIVE: To demonstrate the inhibitory function of the prodomain of tumor necrosis factor-α (TNF-α) converting enzyme (TACE) on TACE activity and to develop an approach to interfere with inflammation processes. METHODS: The cDNA encoding the full-length ectodomain (T1300) and prodomain (T591) of T...

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Detalles Bibliográficos
Autores principales: Li, Xiaoou, Yan, Yuan, Huang, Wei, Yang, Yuzhen
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802003/
https://www.ncbi.nlm.nih.gov/pubmed/20054479
http://dx.doi.org/10.3390/ijms10125442