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Effect of the mechanical activation on size reduction of crystalline acetaminophen drug particles

The decrease in particle size may offer new properties to drugs. In this study, we investigated the size reduction influence of the acetaminophen (C(8)H(9)O(2)N) particles by mechanical activation using a dry ball mill. The activated samples with the average size of 1 μm were then investigated in di...

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Detalles Bibliográficos
Autores principales: Biazar, Esmaeil, Beitollahi, Ali, Rezayat, S Mehdi, Forati, Tahmineh, Asefnejad, Azadeh, Rahimi, Mehdi, Zeinali, Reza, Ardeshir, Mahmoud, Hatamjafari, Farhad, Sahebalzamani, Ali, Heidari, Majid
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802041/
https://www.ncbi.nlm.nih.gov/pubmed/20054432