Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2

AIMS: Prolonged endothelin (ET) receptor signalling causes vasoconstriction and can lead to hypertension, vascular smooth muscle hypertrophy, and hyperplasia. Usually, G protein-coupled receptor signalling is negatively regulated by G protein-coupled receptor kinases (GRKs), preventing prolonged or...

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Detalles Bibliográficos
Autores principales: Morris, Gavin E., Nelson, Carl P., Standen, Nicholas B., Challiss, R.A. John, Willets, Jonathon M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802200/
https://www.ncbi.nlm.nih.gov/pubmed/19748906
http://dx.doi.org/10.1093/cvr/cvp310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802200/
https://www.ncbi.nlm.nih.gov/pubmed/19748906
http://dx.doi.org/10.1093/cvr/cvp310

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