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Down-regulation of transforming growth factor beta-2 expression is associated with the reduction of cyclosporin induced gingival overgrowth in rats treated with roxithromycin: an experimental study

BACKGROUND: Gingival overgrowth (GO) is a common side effect of the chronic use of cyclosporine (CsA), an immunosuppressant widely used to prevent rejection in transplant patients. Recent studies have reported elevated levels of specific cytokines in gingival overgrowth tissue, particularly TGF-beta...

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Detalles Bibliográficos
Autores principales: Condé, Simone Aparecida Probst, Bastos, Marcus Gomes, Vieira, Beatriz Julião, Aarestrup, Fernando Monteiro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802586/
https://www.ncbi.nlm.nih.gov/pubmed/19995419
http://dx.doi.org/10.1186/1472-6831-9-33