A sequence similar to tRNA(3)(Lys) gene is embedded in HIV-1 U3/R and promotes minus strand transfer

We identified a sequence embedded in the U3/R region of HIV-1 RNA that is highly complementary to human tRNA(3)(Lys). The free energy of annealing to tRNA(3)(Lys) is significantly lower for this sequence and the primer-binding site than for other similar length viral sequences. The only interruption...

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Detalles Bibliográficos
Autores principales: Piekna-Przybylska, Dorota, DiChiacchio, Laura, Mathews, David H., Bambara, Robert A.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802660/
https://www.ncbi.nlm.nih.gov/pubmed/19966801
http://dx.doi.org/10.1038/nsmb.1687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802660/
https://www.ncbi.nlm.nih.gov/pubmed/19966801
http://dx.doi.org/10.1038/nsmb.1687

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