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Crystal Structures of the ATPase Domains of Four Human Hsp70 Isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78

The 70-kDa heat shock proteins (Hsp70) are chaperones with central roles in processes that involve polypeptide remodeling events. Hsp70 proteins consist of two major functional domains: an N-terminal nucleotide binding domain (NBD) with ATPase activity, and a C-terminal substrate binding domain (SBD...

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Detalles Bibliográficos
Autores principales: Wisniewska, Magdalena, Karlberg, Tobias, Lehtiö, Lari, Johansson, Ida, Kotenyova, Tetyana, Moche, Martin, Schüler, Herwig
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803158/
https://www.ncbi.nlm.nih.gov/pubmed/20072699
http://dx.doi.org/10.1371/journal.pone.0008625