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Decreased mitochondrial DNA content in blood samples of patients with stage I breast cancer

BACKGROUND: Alterations of mitochondrial DNA (mtDNA) have been implicated in carcinogenesis. We developed an accurate multiplex quantitative real-time PCR for synchronized determination of mtDNA and nuclear DNA (nDNA). We sought to investigate whether mtDNA content in the peripheral blood of breast...

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Detalles Bibliográficos
Autores principales: Xia, Peng, An, Han-Xiang, Dang, Cheng-Xue, Radpour, Ramin, Kohler, Corina, Fokas, Emmanouil, Engenhart-Cabillic, Rita, Holzgreve, Wolfgang, Zhong, Xiao Yan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803198/
https://www.ncbi.nlm.nih.gov/pubmed/20025731
http://dx.doi.org/10.1186/1471-2407-9-454