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15-Deoxy-Δ(12,14)-Prostaglandin J(2) Upregulates the Expression of LPS-Induced IL-8/CXCL8 mRNA in Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats

BACKGROUND: 15d-PGJ(2) has been known to act as an anti-inflammatory agent and has anti-hypertensive effects. As a result of these properties, we examined the effect of 15d-PGJ(2) on the LPS-induced IL-8/CXCL8 mRNA expression in VSMCs from SHR. METHODS: Effect and action mechanism of 15d-PGJ(2) on t...

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Detalles Bibliográficos
Autores principales: Kim, Jung Hae, Kim, Hee Sun
Formato: Texto
Lenguaje:English
Publicado: The Korean Association of Immunobiologists 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803308/
https://www.ncbi.nlm.nih.gov/pubmed/20107546
http://dx.doi.org/10.4110/in.2009.9.2.64