The Orphan Tyrosine Kinase Receptor, ROR2, Mediates Wnt5A Signaling in Metastatic Melanoma

Tyrosine kinase receptors represent targets of great interest for cancer therapy. Here we demonstrate, for the first time, the importance of the orphan tyrosine kinase receptor, ROR2, in melanoma progression. Using melanoma tissue microarrays we show that ROR2 is expressed predominantly in metastati...

Descripción completa

Detalles Bibliográficos
Autores principales: O’Connell, Michael P., Fiori, Jennifer L., Xu, Mai, Carter, Arnell D., Frank, Brittany P., Camilli, Tura C., French, Amanda D., Dissanayake, Samudra K., Indig, Fred E., Bernier, Michel, Taub, Dennis D., Hewitt, Stephen M., Weeraratna, Ashani T.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803338/
https://www.ncbi.nlm.nih.gov/pubmed/19802008
http://dx.doi.org/10.1038/onc.2009.305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803338/
https://www.ncbi.nlm.nih.gov/pubmed/19802008
http://dx.doi.org/10.1038/onc.2009.305

Ejemplares similares