The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth

BACKGROUND: Human clear cell renal cell carcinoma (CRCC) remains resistant to therapies. Recent advances in Hypoxia Inducible Factors (HIF) molecular network led to targeted therapies, but unfortunately with only limited clinical significance. Elucidating the molecular processes involved in kidney t...

Descripción completa

Detalles Bibliográficos
Autores principales: Dormoy, Valérian, Danilin, Sabrina, Lindner, Véronique, Thomas, Lionel, Rothhut, Sylvie, Coquard, Catherine, Helwig, Jean-Jacques, Jacqmin, Didier, Lang, Hervé, Massfelder, Thierry
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803450/
https://www.ncbi.nlm.nih.gov/pubmed/20015350
http://dx.doi.org/10.1186/1476-4598-8-123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803450/
https://www.ncbi.nlm.nih.gov/pubmed/20015350
http://dx.doi.org/10.1186/1476-4598-8-123

Ejemplares similares