MTHFR polymorphisms in gastric cancer and in first-degree relatives of patients with gastric cancer

Two common mutations, 677 C→T and a1298 A→C, in the methylenetetrahydrofolate reductase gene (MTHFR) reduce the activity of MTHFR and folate metabolism. Familial aggregation in a variable but significant proportion of gastric cancer (GC) cases suggests the importance of genetic predisposition in det...

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Detalles Bibliográficos
Autores principales: De Re, Valli, Cannizzaro, R., Canzonieri, V., Cecchin, E., Caggiari, L., De Mattia, E., Pratesi, C., De Paoli, P., Toffoli, G.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803747/
https://www.ncbi.nlm.nih.gov/pubmed/20237899
http://dx.doi.org/10.1007/s13277-009-0004-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803747/
https://www.ncbi.nlm.nih.gov/pubmed/20237899
http://dx.doi.org/10.1007/s13277-009-0004-1

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