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A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q(−) syndrome

The identification of the genes associated with chromosomal translocation breakpoints has fundamentally changed our understanding of the molecular basis of hematological malignancies. By contrast, the study of chromosomal deletions has been hampered by the large number of genes deleted and the compl...

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Detalles Bibliográficos
Autores principales: Barlow, Jillian L., Drynan, Lesley F., Hewett, Duncan R., Holmes, Luke R., Lorenzo-Abalde, Silvia, Lane, Alison L., Jolin, Helen E., Pannell, Richard, Middleton, Angela J., Wong, See Heng, Warren, Alan J, Wainscoat, James S., Boultwood, Jacqueline, McKenzie, Andrew N.J.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803774/
https://www.ncbi.nlm.nih.gov/pubmed/19966810
http://dx.doi.org/10.1038/nm.2063