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A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q(−) syndrome
The identification of the genes associated with chromosomal translocation breakpoints has fundamentally changed our understanding of the molecular basis of hematological malignancies. By contrast, the study of chromosomal deletions has been hampered by the large number of genes deleted and the compl...
Autores principales: | Barlow, Jillian L., Drynan, Lesley F., Hewett, Duncan R., Holmes, Luke R., Lorenzo-Abalde, Silvia, Lane, Alison L., Jolin, Helen E., Pannell, Richard, Middleton, Angela J., Wong, See Heng, Warren, Alan J, Wainscoat, James S., Boultwood, Jacqueline, McKenzie, Andrew N.J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803774/ https://www.ncbi.nlm.nih.gov/pubmed/19966810 http://dx.doi.org/10.1038/nm.2063 |
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