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YQ36: A Novel Bisindolylmaleimide Analogue Induces KB/VCR Cell Death

Overexpression of multidrug resistance proteins P-glycoprotein (P-gp, MDR1) causes resistance of the tumor cells against a variety of chemotherapeutic agents. 3-(1-methyl-1H-indol-3-yl)-1-phenyl-4-(1-(3-(piperidin-1-yl)propyl)-1H-pyrazolo[3,4-b]pyridine-3-yl)-1H-pyrrole-2,5-dione (YQ36) is a novel a...

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Detalles Bibliográficos
Autores principales: Cao, Ji, Zhang, Lei, Ye, Qing, Zhou, Xinglu, Lou, Jianshu, Zhu, Difeng, Hu, Yongzhou, He, Qiaojun, Yang, Bo
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804113/
https://www.ncbi.nlm.nih.gov/pubmed/20069125
http://dx.doi.org/10.1155/2009/535072