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DDIT3/CHOP and the sarcoma fusion oncoprotein FUS-DDIT3/TLS-CHOP bind cyclin-dependent kinase 2

BACKGROUND: The DDIT3 gene encodes a transcription factor belonging to the CCAAT/enhancer binding protein (C/EBP) family. It is normally expressed at very low levels but is activated by cellular stress conditions and induces G1 arrest and, in some cell types, apoptosis. DDIT3 is found as a part of t...

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Detalles Bibliográficos
Autores principales: Bento, Christoffer, Andersson, Mattias K, Åman, Pierre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804592/
https://www.ncbi.nlm.nih.gov/pubmed/20017906
http://dx.doi.org/10.1186/1471-2121-10-89