In vitro suppression of the MMP-3 gene in normal and cytokine-treated human chondrosarcoma using small interfering RNA

BACKGROUND: Matrix metalloproteinase (MMPs) synthesized and secreted from connective tissue cells have been thought to participate in degradation of the extracellular matrix. Increased MMPs activities that degrade proteoglycans have been measured in osteoarthritis cartilage. This study aims to suppr...

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Detalles Bibliográficos
Autores principales: Nganvongpanit, Korakot, Chaochird, Patama, Siengdee, Puntita, Pothacharoen, Peraphan, Klunklin, Kasisin, Chomdej, Siriwadee, Mekchay, Supamit, Kongtaweelert, Prachya
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804682/
https://www.ncbi.nlm.nih.gov/pubmed/20034400
http://dx.doi.org/10.1186/1749-799X-4-45

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804682/
https://www.ncbi.nlm.nih.gov/pubmed/20034400
http://dx.doi.org/10.1186/1749-799X-4-45

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