Human synthetic lethal inference as potential anti-cancer target gene detection

BACKGROUND: Two genes are called synthetic lethal (SL) if mutation of either alone is not lethal, but mutation of both leads to death or a significant decrease in organism's fitness. The detection of SL gene pairs constitutes a promising alternative for anti-cancer therapy. As cancer cells exhi...

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Detalles Bibliográficos
Autores principales: Conde-Pueyo, Nuria, Munteanu, Andreea, Solé, Ricard V, Rodríguez-Caso, Carlos
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804737/
https://www.ncbi.nlm.nih.gov/pubmed/20015360
http://dx.doi.org/10.1186/1752-0509-3-116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804737/
https://www.ncbi.nlm.nih.gov/pubmed/20015360
http://dx.doi.org/10.1186/1752-0509-3-116

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