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Human synthetic lethal inference as potential anti-cancer target gene detection
BACKGROUND: Two genes are called synthetic lethal (SL) if mutation of either alone is not lethal, but mutation of both leads to death or a significant decrease in organism's fitness. The detection of SL gene pairs constitutes a promising alternative for anti-cancer therapy. As cancer cells exhi...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804737/ https://www.ncbi.nlm.nih.gov/pubmed/20015360 http://dx.doi.org/10.1186/1752-0509-3-116 |