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Variable expression of cysteinyl leukotriene type I receptor splice variants in asthmatic females with different promoter haplotypes
BACKGROUND: Cysteinyl leukotrienes are potent inflammatory mediators implicated in the pathogenesis of asthma. Human cysteinyl leukotriene receptor 1 (CYSLTR1) gene contains five exons that are variably spliced. Within its promoter few polymorphisms were described. To date, there has been no evidenc...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805608/ https://www.ncbi.nlm.nih.gov/pubmed/20003473 http://dx.doi.org/10.1186/1471-2172-10-63 |