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Variable expression of cysteinyl leukotriene type I receptor splice variants in asthmatic females with different promoter haplotypes

BACKGROUND: Cysteinyl leukotrienes are potent inflammatory mediators implicated in the pathogenesis of asthma. Human cysteinyl leukotriene receptor 1 (CYSLTR1) gene contains five exons that are variably spliced. Within its promoter few polymorphisms were described. To date, there has been no evidenc...

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Detalles Bibliográficos
Autores principales: Sokolowska, Milena, Wodz-Naskiewicz, Karolina, Cieslak, Malgorzata, Seta, Karolina, Bednarek, Andrzej K, Pawliczak, Rafal
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805608/
https://www.ncbi.nlm.nih.gov/pubmed/20003473
http://dx.doi.org/10.1186/1471-2172-10-63

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