Lack of functional and expression homology between human and mouse aldo-keto reductase 1C enzymes: implications for modelling human cancers

BACKGROUND: Over recent years, enzymes of the aldo-keto reductase (AKR) 1C subfamily have been implicated in the progression of prostate, breast, endometrial and leukemic cancers. This is due to the ability of AKR1C enzymes to modify androgens, estrogens, progesterone and prostaglandins (PGs) in a t...

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Detalles Bibliográficos
Autores principales: Veliça, Pedro, Davies, Nicholas J, Rocha, Pedro P, Schrewe, Heinrich, Ride, Jonathan P, Bunce, Chris M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805611/
https://www.ncbi.nlm.nih.gov/pubmed/20003443
http://dx.doi.org/10.1186/1476-4598-8-121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805611/
https://www.ncbi.nlm.nih.gov/pubmed/20003443
http://dx.doi.org/10.1186/1476-4598-8-121

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