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RNA degradation compromises the reliability of microRNA expression profiling
BACKGROUND: MicroRNAs are small non-coding RNAs that post-transcriptionally regulate gene expression and their expression is frequently altered in human diseases, including cancer. To correlate clinically relevant parameters with microRNA expression, total RNA is frequently prepared from samples tha...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805631/ https://www.ncbi.nlm.nih.gov/pubmed/20025722 http://dx.doi.org/10.1186/1472-6750-9-102 |