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RNA degradation compromises the reliability of microRNA expression profiling

BACKGROUND: MicroRNAs are small non-coding RNAs that post-transcriptionally regulate gene expression and their expression is frequently altered in human diseases, including cancer. To correlate clinically relevant parameters with microRNA expression, total RNA is frequently prepared from samples tha...

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Detalles Bibliográficos
Autores principales:	Ibberson, David, Benes, Vladimir, Muckenthaler, Martina U, Castoldi, Mirco
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Methodology article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805631/ https://www.ncbi.nlm.nih.gov/pubmed/20025722 http://dx.doi.org/10.1186/1472-6750-9-102

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