Presynaptic CaV2 calcium channel traffic requires CALF-1 and the alpha2-delta subunit UNC-36

Presynaptic voltage-gated calcium channels provide calcium for synaptic vesicle exocytosis. We show here that a GFP-tagged alpha1 subunit of the C. elegans CaV2 channel, UNC-2, is localized to presynaptic active zones of sensory and motor neurons. Synaptic localization of CaV2 requires the alpha2-de...

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Detalles Bibliográficos
Autores principales: Saheki, Yasunori, Bargmann, Cornelia I.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805665/
https://www.ncbi.nlm.nih.gov/pubmed/19718034
http://dx.doi.org/10.1038/nn.2383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805665/
https://www.ncbi.nlm.nih.gov/pubmed/19718034
http://dx.doi.org/10.1038/nn.2383

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