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Functional consequences of mutations in the Drosophila histamine receptor HCLB

The gene hclB encodes a histamine-gated chloride channel subunit in Drosophila melanogaster. Mutations in hclB lead to defects in the visual system and altered sensitivity to the action of ivermectin. To investigate whether this member of the Cys-loop receptors is common across the Insecta, we analy...

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Detalles Bibliográficos
Autores principales: Yusein, Shazie, Wolstenholme, Adrian, Semenov, Eugene
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805722/
https://www.ncbi.nlm.nih.gov/pubmed/19716373
http://dx.doi.org/10.1016/j.jinsphys.2009.08.016