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Positional dependence of transcriptional inhibition by DNA torsional stress in yeast chromosomes
How DNA helical tension is constrained along the linear chromosomes of eukaryotic cells is poorly understood. In this study, we induced the accumulation of DNA (+) helical tension in Saccharomyces cerevisiae cells and examined how DNA transcription was affected along yeast chromosomes. The results r...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805846/ https://www.ncbi.nlm.nih.gov/pubmed/20057354 http://dx.doi.org/10.1038/emboj.2009.391 |