Cargando…

Positional dependence of transcriptional inhibition by DNA torsional stress in yeast chromosomes

How DNA helical tension is constrained along the linear chromosomes of eukaryotic cells is poorly understood. In this study, we induced the accumulation of DNA (+) helical tension in Saccharomyces cerevisiae cells and examined how DNA transcription was affected along yeast chromosomes. The results r...

Descripción completa

Detalles Bibliográficos
Autores principales: Joshi, Ricky S, Piña, Benjamin, Roca, Joaquim
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805846/
https://www.ncbi.nlm.nih.gov/pubmed/20057354
http://dx.doi.org/10.1038/emboj.2009.391