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Ascorbic Acid Potentiation of Arsenic Trioxide Anticancer Activity Against Acute Promyelocytic Leukemia

INTRODUCTION: Acute promyelocytic leukemia (APL) is a malignant disorder of the white blood cells. Arsenic trioxide (As(2)O(3)) has been used as a therapeutic agent to treat APL and other tumors. Studies suggest that ascorbic acid (AA) supplementation may improve the clinical outcome of As(2)O(3) fo...

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Detalles Bibliográficos
Autores principales: Yedjou, Clement, Thuisseu, Laurette, Tchounwou, Christine, Gomes, Maria, Howard, Carolyn, Tchounwou, Paul
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Inc 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805867/
https://www.ncbi.nlm.nih.gov/pubmed/20098508
http://dx.doi.org/10.1111/j.1753-5174.2009.00022.x