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Targeting of inositol 1,4,5-trisphosphate receptor to the endoplasmic reticulum by its first transmembrane domain

Targeting of IP(3)R (inositol 1,4,5-trisphosphate receptors) to membranes of the ER (endoplasmic reticulum) and their retention within ER or trafficking to other membranes underlies their ability to generate spatially organized Ca(2+) signals. N-terminal fragments of IP(3)R1 (type 1 IP(3)R) were tag...

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Detalles Bibliográficos
Autores principales: Pantazaka, Evangelia, Taylor, Colin W.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805921/
https://www.ncbi.nlm.nih.gov/pubmed/19845505
http://dx.doi.org/10.1042/BJ20091051