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Targeting of inositol 1,4,5-trisphosphate receptor to the endoplasmic reticulum by its first transmembrane domain
Targeting of IP(3)R (inositol 1,4,5-trisphosphate receptors) to membranes of the ER (endoplasmic reticulum) and their retention within ER or trafficking to other membranes underlies their ability to generate spatially organized Ca(2+) signals. N-terminal fragments of IP(3)R1 (type 1 IP(3)R) were tag...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805921/ https://www.ncbi.nlm.nih.gov/pubmed/19845505 http://dx.doi.org/10.1042/BJ20091051 |