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Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells

Human tumors and cultured cells contain elevated levels of endogenous DNA damage resulting from telomere dysfunction, replication and transcription errors, reactive oxygen species, and genome instability. However, the contribution of telomere-associated versus telomere-independent endogenous DNA les...

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Detalles Bibliográficos
Autores principales: Nakamura, Asako J., Redon, Christophe E., Bonner, William M., Sedelnikova, Olga A.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806003/
https://www.ncbi.nlm.nih.gov/pubmed/20157510