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A screen of apoptosis and senescence regulatory genes for life span effects when over-expressed in Drosophila

Conditional expression of transgenes in Drosophila was produced using the Geneswitch system, wherein feeding the drug RU486/Mifepristone activates the artificial transcription factor Geneswitch. Geneswitch was expressed using the Actin5C promoter and this was found to yield conditional, tissue-gener...

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Detalles Bibliográficos
Autores principales: Shen, Jie, Curtis, Christina, Tavaré, Simon, Tower, John
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806004/
https://www.ncbi.nlm.nih.gov/pubmed/20157509