Sequence-specific processing of telomeric 3' overhangs by the Werner syndrome protein exonuclease activity

Werner syndrome is a premature aging disease caused by loss of function mutations in the Werner syndrome protein (WRN) gene. WRN is a RecQ helicase that in contrast to every other member of this family of proteins possesses an exonuclease activity. The findings that cells lacking WRN activity displa...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Baomin, Reddy, Sita, Comai, Lucio
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806009/
https://www.ncbi.nlm.nih.gov/pubmed/20157518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806009/
https://www.ncbi.nlm.nih.gov/pubmed/20157518

Ejemplares similares