Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging

Poly(ADP-ribose) polymerase 1 (PARP1) is a chromatin-associated nuclear protein, which functions as molecular stress sensor. Reactive oxygen species, responsible for the most plausible and currently acceptable global mechanism to explain the aging process, strongly activate the enzymatic activity of...

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Detalles Bibliográficos
Autores principales: Altmeyer, Matthias, Hottiger, Michael O.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806023/
https://www.ncbi.nlm.nih.gov/pubmed/20157531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806023/
https://www.ncbi.nlm.nih.gov/pubmed/20157531

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